List of the latest papers published acknowledging RADDEL

This is the list of papers acknowledging RADDEL project that have been published in the past few months:


C. Spinato, A.C. Ruiz de Garibay, M.  Kierkowicz, E. Pach, M. Martincic, R. Klippstein, M. Bourgognon, J.T-W. Wang, C. Ménard-Moyon, K.T. Al-Jamal, B. Ballesteros, G. Tobias and A. Bianco    

Design of antibody-functionalized carbon nanotubes filled with radioactivable metals towards a targeted anticancer therapy  

Nanoscale, in press (2016)

DOI: 10.1039/C5NR07923C

Collaborative paper from RADDEL partners KCL, ICN, CSIC and CNRS



M. Kierkowicz, E. Pach, A. Santidrián, E. Tobías-Rossell, M. Kalbác, B. Ballesteros and G. Tobias    

Effect of Steam-Treatment Time on the Length and Structure of Single-Walled and Double-Walled Carbon Nanotubes  

ChemNanoMat, early view (2016)

DOI: 10.1002/cnma.201500207

Collaborative paper from RADDEL partners HIPC, ICN and CSIC



D. Emfietzoglou, I. Kyriakou, R. García-Molina and I. Abril    

Inelastic mean free path of low-energy electrons in condensed media: beyond the standard models  

Surf. Interf. Anal., early view (2016)

DOI: 10.1002/sia.5878

Paper from RADDEL partner UOI



J.T-W. Wang, N. Rubio, H. Kafa, E. Venturelli, C. Fabbro, C. Ménard-Moyon, T. Da Ros, J.K. Sosabowski, A.D. Lawson, M.K. Robinson, M. Prato, A. Bianco, F. Festy, J.E. Preston, K. Kostarelos, K. T. Al-Jamal      

Kinetics of functionalised carbon nanotube distribution in mouse brain after systemic injection: Spatial to ultra-structural analyses  

J. Controlled Rel., 224, 22-32 (2016)

DOI: 10.1016/j.jconrel.2015.12.039

Collaborative paper from RADDEL partners UNITS, CNRS and KCL



C. Spinato, D. Giust, I.A. Vacchi, C. Ménard-Moyon, K. Kostarelos and A. Bianco    

Different Chemical Strategies to Aminate Oxidised Multi-Walled Carbon Nanotubes for siRNA Complexation and Delivery  

J. Mater. Chem. B4, 431-441 (2016)

DOI: 10.3791/52989

Collaborative paper from RADDEL partners UNIMAN and CNRS



M. Martincic, E. Pach, B. Ballesteros and G. Tobias    

Quantitative Monitoring of the Removal of Non-Encapsulated Material External to Filled Carbon Nanotube Samples 

Phys. Chem. Chem. Phys.17, 31662-31669 (2015)

DOI: 10.3791/52989

Collaborative paper from RADDEL partners ICN and CSIC



M. Bourgognon, R. Klippstein and K. T. Al-Jamal    

Kupffer Cell Isolation for Nanoparticle Toxicity Testing

J. Vis. Exp., Aug 18;(102):e52989 (2015)

DOI: 10.3791/52989

Paper from RADDEL partner KCL



H. Kafa, J.T-W. Wang, N. Rubio, K. Venner, G. Anderson, E. Pach, B. Ballesteros, J. E. Preston, N. J. Abbott and K. T. Al-Jamal    

The interaction of carbon nanotubes with an in vitro blood-brain barrier model and mouse brain in vivo

Biomaterials, 53, 437-452 (2015)

DOI: 10.1016/j.biomaterials.2015.02.083

Collaborative paper from RADDEL partners ICN and KCL



R. Klippstein, J.T-W. Wang, R.I. El- Gogary, J. Bai, F. Mustafa, N. Rubio, S. Bansal, W.T. Al-Jamal and K. T. Al-Jamal    

Passively Targeted Curcumin-Loaded PEGylated PLGA Nanocapsules for Colon Cancer Therapy In Vivo 

Small, 11(36), 4704-4722 (2015)

DOI: 10.1002/smll.201403799

Paper from RADDEL partner KCL



J.M. González-Domínguez, A. Santidrián, A. Criado, C. Hadad, M. Kalbác and T. Da Ros    

Multipurpose Nature of Rapid Covalent Functionalization on Carbon Nanotubes 

Chem. Eur. J., 21(51), 18631-18641 (2015)

DOI: 10.1002/chem.201503085

Collaborative paper from RADDEL partners UNITS and HIPC



C. Annese, L. D'Accolti, V. Armuzza, T. Da Ros and C. Fusco    

Epoxidation of Multi-Walled Carbon Nanotubes by Organocatalytic Oxidation 

Eur. J. Org. Chem., 14, 3063-2068 (2015)

DOI: 10.1002/ejoc.201500107

Paper from RADDEL partner UNITS



K-C. Mei, Y. Guo, J. Bai, P.M. Costa, H. Kafa, A. Protti, R.C.Hider and K. T. Al-Jamal    

Organic Solvent-Free, One-Step Engineering of Graphene-Based Magnetic-Responsive Hybrids Using Design of Experiment-Driven Mechanochemistry

ACS Appl. Mater. Interfaces, 7 (26), 14176-14181 (2015)

DOI: 10.1021/acsami.5b03577

Paper from RADDEL partner KCL



N. Rubio, K-C. Mei, R. Klippstein, P.M. Costa, N. Hodgins, J.T-W. Wang, F. Festy, V. Abbate, R.C.Hider, K.L.A. Chan and K. T. Al-Jamal    

Solvent-Free Click-Mechanochemistry for the Preparation of Cancer Cell Targeting Graphene Oxide 

ACS Appl. Mater. Interfaces, 7 (34), 18920-18923 (2015)

DOI: 10.1021/acsami.5b06250

Paper from RADDEL partner KCL



L. Cabana, A. González-Campo, X. Ke, G. Van Tendeloo, R. Nuñez and G. Tobias

Efficient Chemical Modification of Carbon Nanotubes with Metallacarboranes 

Chem. Eur. J., 21 (47), 16792-16795 (2015)

DOI: 10.1002/chem.201503096

Collaborative paper from RADDEL partners CSIC and EMAT


Several papers from RADDEL partners published in the last few months

This is the list of papers featuring one or more RADDEL partners that have been published in the past few months:


Alessia Battigelli , Cécilia Ménard-Moyon and Alberto Bianco

Carbon nanomaterials as new tools for immunotherapeutic applications

J. Mater. Chem. B, 2, 6144-6156 (2014)

DOI: 10.1039/C4TB00563E

Review article from RADDEL partner CNRS


Iris Marangon, Cécilia Ménard-Moyon, Jelena Kolosnjaj-Tabi, Marie Lys Béoutis, Lénaic Lartigue, Damien Alloyeau, Elzbieta Pach, Belén Ballesteros, Gwennhael Autret, Tsedev Ninjbadgar, Dermot F. Brougham, Alberto Bianco, Florence Gazeau

Covalent Functionalization of Multi-walled Carbon Nanotubes with a Gadolinium Chelate for Efficient T1-Weighted Magnetic Resonance Imaging

Advanced Functional Materials, 24 (45), 7173–7186 (2014)

DOI: 10.1002/adfm.201402234

Collaborative paper including RADDEL partners CNRS and ICN


Noelia Rubio, Rui Serra-Maia, Houmam Kafa, Kuo-Ching Mei, Elzbieta Pach, William Luckhurst, Mire Zloh, Frederic Festy, Jonathan P. Richardson, Julian R. Naglik, Belén Ballesteros, and Khuloud T. Al-Jamal

Production of Water-Soluble Few-Layer Graphene Mesosheets by Dry Milling with Hydrophobic Drug

Langmuir, 30 (49), 14999–15008 (2014)

DOI: 10.1021/la5038475

Collaborative paper including RADDEL partners KCL and ICN


Markus Martincic, Gerard Tobias

Filled carbon nanotubes in biomedical imaging and drug delivery

Expert Opinion on Drug Delivery, 12 (4) , 563-581 (2015)

DOI: 10.1517/17425247.2015.971751

Review article from RADDEL partner CSIC


Sonia De Munari, Torben Schiffner, Benjamin G. Davis

A Triply Divergent Reagent for Glycoprotein Synthesis

Israel Journal of Chemistry (Special Issue: Carbohydrate Chemistry), 55 (3-4), 387–391 (2015)

DOI: 10.1002/ijch.201400182

Research article from RADDEL partner UOX


Martin Šefl, Sébastien Incerti, George Papamichael, Dimitris Emfietzoglou

Calculation of cellular S-values using Geant4-DNA: The effect of cell geometry

Applied Radiation and Isotopes, 104, 113–123 (2015)

Research article from RADDEL partner UoI


Laura Cabana, Xiaoxing Ke, Dejan Kepic, Judith Oro-Solé, Ester Tobías-Rossell, Gustaaf Van Tendeloo, Gerard Tobias

The role of steam treatment on the structure, purity and lenght distribution of multi-walled carbon nanotubes 

Carbon, 93, 1059-1067 (2015)

Collaborative paper including RADDEL partners CSIC and UA




A paper from RADDEL partner UOX, available as advanced article in Chem. Commun.

Reida N. Rutte, Thomas. B. Parsons, Benjamin G. Davis

Modification of fulleropyrazolines modulates their cleavage by light

Chem. Commun., advance article (2014)
DOI: 10.1039/C4CC03859B  




This paper deals with the extraordinary electrochemistry and the tunability of the energy levels for fulleropyrazolines, which allow their use in photovoltaics and charge-transfer systems. The team at the University of Oxford (UOX) in United Kingdom is investigating different methods of photo-controlled release for fullerene systems as part of RADDEL project to use fullerenes as removable corks for encapsulation of radioactive moieties inside carbon nanotubes. One ESR fellow recruited by UOX is working on this.               

A collaborative paper between RADDEL partners KCL and EMAT, published in ACS Nano

R. I. El-Gogary, N. Rubio, J. T-W. Wang, W. T. Al-Jamal, M. Bourgognon, H, Kafa, M. Naeem, R. Klippstein, V. Abbate, F. Leroux, S. Bals, G. Van Tendeloo, A. O. Kamel, G. A. S. Awad, N. D. Mortada, K. T. Al-Jamal 

Polyethylene Glycol Conjugated Polymeric Nanocapsules for Targeted Delivery of Quercetin to Folate-Expressing Cancer Cells in Vitro and in Vivo

ACS Nano, 8, 1384-1401 (2014)


In this paper, the formulation and characterization of chemically modified polymeric nanocapsules incorporating the anticancer drug quercetin for the passive and active targeting to tumours is described. The developed nanocapsules provide a system for targeted delivery of a range of hydrophobic anticancer drugs in vivo. RADDEL partners KCL and EMAT have participated in this study that provide new insights into the in vivo behaviour of nanocapsules.                       

A collaborative paper from CSIC and ICN on the effect of ultraviolet pulsed laser irradiation on MWCNTs, just published on the Journal of Applied Physics

A. Pérez del Pino, E. György, L. Cabana, B. Ballesteros, G. Tobias

Ultraviolet pulsed laser irradiation on multi-walled carbon nanotubes in nitrogen atmosphere

Journal of Applied Physics, 115, 093501 (2014)



Laser irradiation of randomly oriented multi-walled carbon nanotube (MWCNT) networks has been carried out using a pulsed Nd:YAG UV laser in nitrogen gas environment. The evolution of the MWCNT morphology and structure as a function of laser fluence and number of accumulated laser pulses has been studied using electron microscopies and Raman spectroscopy. The results and knowledge generated from this work will be used by RADDEL network to understand the behavior under irradiation of carbon nanotubes filled with radioactive materials.            

A paper from RADDEL partners CSIC and ICN dealing with the filling of CNTs, available as early view in the journal Advanced Materials,

L. Cabana, B. Ballesteros, E. Batista, C. Magen, L. Arenal, J. Oró-Solé, R. Rurali, G. Tobias

Synthesis of PbI2 single-layered inorganic nanotubes encapsulated within carbon nanotubes

Advanced Materials, 26, 2016-2021 (2014)


This paper deals with the template-assisted growth of single layered PbI2 nanotubes using carbon nanotubes as hosting templates. The results and knowledge generated from this work is now being used by the RADDEL team at the Institute of Materials Science of Barcelona (ICMAB-CSIC) to encapsulate other inorganic materials with interest in biomedical applications.     

Collaboration between RADDEL partners CSIC, KCL and EMAT, early view in the journal Advanced Functional Materials

J. Wang, L. Cabana, M. Bourgagnon, H. Kaffa, A. Protti, K. Venner, A. Shah, J. Sosabowski, S. Mather, A. Roig, S. Ke, G. Van Tendeloo, R. de Rosales, G. Tobias, K. T. Al-Jamal

Magnetically Decorated Multi-Walled Carbon Nanotubes as Dual MRI and SPECT Contrast Agents

Advanced Functional Materials, 24, 1880-1894 (2014)

In the work carried out for this paper, the teams from CSIC (Spain), KCL (UK) and EMAT (Belgium) developed radio-labeled, iron oxide-decorated multiwalled CNTs (MWNTs) as dual magnetic resonance (MR) and single photon emission computed tomography (SPECT) contrast agents. RADDEL ESR fellow Maxime Bourgognon from King's College London (UK) helped in the development of the in-vitro toxicity assays to test the toxicity of CNTs. These findings will now be extrapolated and applied in RADDEL project for the functionalised nanocapsules filled with radioactive materials.                        

A review from partners CNRs and UNITS on CNTs for biomedical applications, in press

A. Battigelli, C. Ménard-Moyon, T. Da Ros, M. Prato, A. Bianco

Endowing carbon nanotubes with biological and biomedical properties by chemical modifications

Advanced Drug Delivery Reviews, 65, 1899-1920 (2013)


This review, a collaboration between RADDEL partners UNITS (Italy) and CNRS (France), deals with the different chemical modifications that are available for carbon nanotubes in order to impart specific properties to this material for biological and medical purposes. Some of the functionalization strategies mentioned in this review are being applied by these two partners in the project in order to improve the biocompatibility of CNTs and increase the capacity to conjugate biologically relevant molecules for the apllication of filled nanocapsules in cancer therapy and imaging.                     

A paper from RADDEL partner UOI, published in the Journal of Applied Physics

D. Emfietzoglou, I. Kyriakou, R. Garcia-Molina, I. Abril

The effect of static many-body local-field corrections to inelastic electron scattering in condensed media

Journal of Applied Physics 114, 144907 (2013)



This paper deals with some advanced aspects of the physics of inelastic scattering of low-energy electrons (with energies similar to Auger electrons) in bulk amorphous carbon. The team at the University of Ioannina (UOI) in Greece is now extending the work to low-dimensional systems, in particular carbon nanotubes. The results for CNTs will be then implemented to the Monte Carlo code being developed as part of RADDEL project for running more accurate simulations of the interaction of low-energy electrons with CNTs. The ESR fellow from UOI is currently working on this.